Observational study of a gauze medication contaning Rigenase® and polyhexanide in the treatiment of venous leg ulcers (<6cm2) and perilesional skin

Submitted: May 16, 2022
Accepted: June 27, 2022
Published: July 29, 2022
Abstract Views: 512
PDF: 125
PDF (Italiano): 320
Appendix (Italiano): 40
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Authors

The Triticum Vulgare Extract (TVE) is a particular wheat extract patented by Farmaceutici Damor. TVE (Rigenase®) has been shown to have an important bio stimulation effect promoting the tissue repairing process in vitro. In this context, an observational study was developed to access the effects of a gauze based on Rigenase® and polyhexanide in the treatment of venous ulcers (area <6 cm2 and not beyond the dermal layer) and of damaged perilesional skin whose damage could have also been determined by iatrogenic cause. Inclusion and exclusion criteria were identified and a medication protocol was applied. The study showed that the product based on Rigenase® and polyhexanide is effective in the treatment of venous ulcers and damaged perilesional skin.

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Citations

Funel N, Dini V, Janowska A, et al. Triticum vulgare extract modulates protein-kinase B and matrix metalloproteinases 9 protein expression in BV-2 cells: Bioactivity on inflammatory pathway associated with molecular mechanism wound healing. Mediators Inflamm 2020;2020:2851949. DOI: https://doi.org/10.1155/2020/2851949
Sanguigno L, Casamassa A, Funel N, et al. Triticum vulgare extract exerts an anti-inflammatory action in two in vitro models of inflammation in microglial cells. PLoS One 2018;13:e0197493. DOI: https://doi.org/10.1371/journal.pone.0197493
Tito A, Minale M, Riccio S, et al. A Triticum vulgare extract exhibits regenerating activity during the wound healing process. Clin Cosmet Investig Dermatol 2020;13:21-30. DOI: https://doi.org/10.2147/CCID.S216391
D’Agostino A, Pirozzi AVA, Finamore R, et al. Molecular mechanisms at the basis of pharmaceutical grade Triticum vulgare extract efficacy in prompting keratinocytes healing. Molecules 2020;25:431. DOI: https://doi.org/10.3390/molecules25030431
Antonucci I, Fiorentino G, Contursi P, et al. Antioxidant capacity of Rigenase®, a specific aqueous extract of Triticum vulgare. Antioxidants (Basel) 2018;7:67. DOI: https://doi.org/10.3390/antiox7050067
Atkin L, Bućko Z, Conde Montero E, et al. Implementing TIMERS: The race against hard-to-heal wounds. J Wound Care 2019;23:S1-S50. DOI: https://doi.org/10.12968/jowc.2019.28.Sup3a.S1
Stillo F, Ebner H, Lanza G, et al. Linee Guida SICVE/SIF 2016. Ital J Vasc Endovasc Surg 2016;3:1-45.

How to Cite

Petrella, F., Nebbioso, G., Aquino, M., Bellisi, M., Carella, S., Catalfamo, R. G., … Scanguzzi, A. (2022). Observational study of a gauze medication contaning Rigenase® and polyhexanide in the treatiment of venous leg ulcers (<6cm2) and perilesional skin. Italian Journal of Wound Care, 6(2). https://doi.org/10.4081/ijwc.2022.89

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